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Grasso C, Fabre M-S, Collis SV, Castro ML, Field CS, Schleich N, et al

Analysis of the therapeutic functions of novel melanocortin receptor agonists in mc3r- and mc4r-deficient C57bl/6j mice

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Gene profiling data demonstrated a clear upregulation of multiple Nrf2 regulated genes such as glutamate-cysteine ligase and glutathione-S- transferase, indicating Nrf2 activation that could be triggered by the increase of SQSTM1/p62 due to autophagy inhibition

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