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This is a common issue with bioavailability the measure of how much of a substance actually enters your circulation to have an effect

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Serial dilutions of dihexa in 50% DMSO or water (for dilutions of 50 g/mL or less) were prepared from the stock used to dose the animals to be used for preparation of a standard curve

However, the reality is far from more complex than what marketing suggests, especially when these products are injected for cosmetic purposes

N Engl J Med 1995