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Influence of Age on Drug Responses Variation in drug responses may be due to several factors such as: Diminished cardiac output: A reduction in cardiac output reduces hepatic perfusion which may decrease delivery of drug to the liver for metabolism

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Conversely in the colonic mucosa, GLP-1 co-localizes with PYY, CCK and the orexigenic Insulin-Like peptide 5 (INSL5) (4, 43, 45, 53, 56, 57)

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Bolsters Antioxidant Action* Glutathione is a tri-peptide composed of the three amino acids: L-glutamic acid, L-cysteine and L-glycine