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Complete loss of GPX4 is incompatible with viability, and pharmacological or genetic GPX4 inhibition is widely exploited to induce ferroptosis in cells and tissues

Data were low-pass filtered at 2 kHz and a 5-ms template (2 ms baseline, 2 pA amplitude, 0.5 ms rise time, and 1 ms decay time) was used to detect spontaneous EPSCs

Okumura H, Araragi Y, Nishioka K, Yamashita R, Suzuki T, Watanabe H, et al

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J Med Chem 32:548555 Lazar AC, Wang L, Blttler WA, Amphlett G, Lambert JM, Zhang W (2005) Analysis of the composition of immunoconjugates using size-exclusion chromatography coupled to mass spectrometry