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It could be speculated that this increased discontinuation rate vs all comparators, including GLP-1 RAs, may be possibly attributed to the severity of gastrointestinal adverse events experienced with tirzepatide 15 mg, considering that the incidence of gastrointestinal adverse events was similar between tirzepatide and GLP-1 RAs

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Because both medicines influence central pathways, clinicians typically move slowly, maintain one stable dose, and track changes in vitals and sleep

Direct the water stream down the side of the vial, not directly onto the peptide cake, to prevent damage to the molecular structure