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The study was registered at (NCT05446961) and was conducted in accordance with Good Clinical Practice Guidelines (GCP) and Brazilian National Health Council resolution 466/2021

Aberrant transferrin and ferritin upregulation elicits iron accumulation and oxidative inflammaging causing ferroptosis and undermines estradiol biosynthesis in aging rat ovaries by upregulating NF-b-Activated inducible nitric oxide synthase: first demonstration of an intricate mechanism

The primary downside to iron supplementation is gastrointestinal side effects such as constipation, nausea, and abdominal pain

Schfer et al., 1997, 1998

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