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It is also approved to reduce the risk of major adverse cardiovascular events in adults who have cardiovascular disease and are either overweight or have obesity

Despite decades of public health efforts, obesity increases

Combined with proper diet and exercise, it can accelerate weight-loss progress

Gastrointestinal disturbances may be attributed to semaglutide delaying gastric emptying, in conjunction with affecting gastric inhibitory polypeptide levels

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The guidance was updated for clarity and to be more unambiguous regarding the recommendation to continue these medications and to not cease them prior to the procedure