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A 2025 analysis by the Employers Health Coalition found that 64% of large employers (5,000+ employees) excluded GLP-1 medications for obesity from their health plans, citing projected costs of $12,000 to $15,000 per patient per year (Jain et al., Health Affairs 2025)

But the side effects will be overwhelming

However, unlike small molecules, peptide therapeutics are structurally complex and highly sensitive to manufacturing conditions

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Many people stay on the medication for 6 to 12 months, while others use it longer, taper off, or transition to another option based on what feels sustainable