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[DOI] [PMC free article] [PubMed] [Google Scholar] 106.Adams M.K., Simpson J.A., Richardson A.J., English D.R., Aung K.Z., Makeyeva G.A., Guymer R.H., Giles G.G., Hopper J., Robman L.D., et al

Medical supervision and monitoring is recommended

The researchers note that all 25 of the studies were at high risk of bias, and they would like to see larger independently funded trials in the future to confirm their results

[115] subsequently found circulating irisin levels were significantly lower in PWS patients than in BMI-matched controls

Heard et al

Obesity can affect cancer survivors in various ways, including the chance of cancer recurrence and overall quality of life