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Both ingredients maintain good safety profiles when used appropriately, but l-citrulline's superior tolerance makes it preferable for long-term supplementation protocols

doi: 10.1016/j.ejphar.2021.174310 47 HansenDVHansonJEShengM

doi: 10.3168/jds.2015-10525 Summary Keywords bovine, bypass amino acid, epigenetic, fetal programming, immune system, N retention, performance, reproduction Citation Costa TC, Nascimento KB, Dans MAC, Gionbelli MP and Duarte MS (2025) Rumen-protected methionine for dairy and beef cattle: current perspectives on methionine role, supplementation strategies, metabolism, health, and performance