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Staying well-hydrated is particularly important when taking tirzepatide

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When to Consider Alternatives or Adjunctive Approaches If you have been on stable semaglutide for 3+ months with minimal weight loss or plateau after initial response, your provider may explore dose escalation, compound alternatives (such as compounded tirzepatide or GLP-Squared dual compounds), or concurrent biomarker optimization

The Poisson model provided the best fit, highlighting a significant change in reporting trends after FDA approval

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