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[DOI] [PubMed] [Google Scholar] Tauqir S., Israr M., Rauf B., Malik M.O., Habib S.H., Shah F.A., Usman M., Raza M.A., Shah I., Badshah H., Ehtesham E., Shah M

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

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Patients can remain on these medications indefinitely, and the clinical data supporting long-term use extends to multiple years

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Regular monitoring and appropriate dose adjustment of levothyroxine to maintain TSH within the reference range (typically 0.4-4.0 mU/L, though individualised targets may apply) is essential before implementing additional weight management interventions