This will help your therapist understand where you are and how youre feeling
Most people handle the starting dose reasonably well
2013, no statistically significant changes in IGF-1 or fasting glucose were detected versus placebo
Indeed, growing evidence suggests that women tend to achieve more pronounced glycaemic improvements and greater weight reduction when treated with GLP-1 RAs compared to men, partly explaining the more frequent initiation of GLP-1 therapy among female patients [20, 21]
More than a century ago, patients would get worse and worse until they died
While the nephroprotective effects of SGLT2i were initially derived from secondary endpoints of CV outcome trials (CVOTs), direct confirmation came from dedicated kidney focused trials: CREDENCE (Perkovic et al NEJM 2019| NephJC Summary), DAPA-CKD (Heerspink et al NEJM 2020| NephJC Summary) and finally EMPAKIDNEY (Herrington et al NEJM 2023| NephJC Summary)