[49] Giorgi VS, Da Broi MG, Paz CC, Ferriani RA, Navarro PA
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Writing and editing of the manuscript: all authors
Further studies are needed to clarify the relative antioxidant power and role in microbiota maintenance of glutathione, ascorbic acid, uric acid, proteins, including glutathione-associated enzymes (glutathione-S-transferase (GST) and glutathione peroxidase (GPX)), alpha-tocopherol 38 , beta-carotene 38 and gut bilirubin derivatives (urobilin, stercobilin and protoporphyrin) 39 in the gut
GPX4-ablation in mice and cells revealed downstream 12/15-lipoxygenase-derived lipid peroxidation, trigger apoptosis-inducing factor-mediated cell death, and subsequent oxidative stress (Seiler et al., 2008)
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