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Choose tirzepatide if: You need to lose 40+ pounds The extra 5-7% body weight loss from tirzepatide matters more when you have substantial weight to lose

CSD has been demonstrated to activate the trigeminovascular system (TVS) both centrally and peripherally by exposing the dura to inflammatory molecules, indicating that susceptibility to CSD may contribute to the initiation of migraine attacks (26, 27)

But it can also be caused by inflammation, injuries and certain medications

The long and short

Nausea, vomiting, constipation, and appetite suppression occur with semaglutide, tirzepatide, and retatrutide, though timing and severity vary

Moein personally reviews the results with the patient to determine the best course of action