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Is There a Downside to Taking Berberine

For a research compound like Retatrutide that comes in a 12 mg vial, you're almost certainly going to be drawing multiple smaller doses over time

Light Sensitivity: GLP-1 research peptides should be kept in amber vials or stored in total darkness to prevent photo-oxidation of sensitive amino acids like tryptophan or tyrosine

Scirica BM, Bhatt DL, Braunwald E, et al

Sure, one may be more effective at weight loss (tirzepatide), but that doesnt make it inherently better. Plus, your healthcare provider is the best person to help you determine which medication makes the most sense for you