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GLP-1 is an incretin hormone that enhances insulin secretion in response to meals and promotes satiety

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When the gut lining is damaged by viral persistence or systemic inflammation, the cellular turnover rate must increase to repair the tissue

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In the latter study (94), Ex-4 was found to exert neuroprotective effects in both aged T2DM/obese and healthy mice by administrating a dose of 50 mg/kg Ex-4 from 1.5 or 3 h after MCAO