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Kim, S.H

These formed MSU crystals can stimulate the release of various inflammatory factors, including TNF-, IL-6, and IL-1, which is achieved by activating the NF-B signaling pathway [5]

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An increased mitochondrial respiratory activity in the liver therefore speeds up the degradation and prevents the accumulation of fatty acids in the liver, which prevents the development of fibrosis in MASH [15]

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