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The culture medium was replaced with various concentrations of G extract, D-CuP solution, G/D-CuP extract and blank medium (blank control group, BC) (100 L) (n = 4)

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337 Although all cell types responded to this inhibitor in vitro and showed promising therapeutic effects in vivo, 337 phase I clinical trials for treating advanced solid tumors ultimately failed due to cardiovascular toxicity and wide variability in patient responses

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