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The microscopy images showed cell rupture and lysis (H&E stain), indicative of signs of cell death (TUNEL stain) in the tumor tissue (Fig

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In still further embodiments, the otic gel formulations are applied at or near the round window membrane via a microinjection device

CJC-1295-related bulk drug substances (CJC-1295 [free base], CJC-1295 acetate, CJC1295 with drug affinity complex [DAC] [free base], CJC-1295 DAC acetate, and CJC-1295 DAC trifluoroacetate [TFA])

Its these differences that can influence how individual peptides respond to factors such as moisture, changes in temperature, and oxidation, during storage (Furman et al., 2015)