Lipodystrophy is common among HIV/AIDS patients
On the other hand GPx3 is negatively correlated with MAPK oncogenic signaling pathway (94), which suggests a potential antitumor effect in thyroid cancer, while a decrease in GPx3 levels predisposes to an increase in the size of primary tumors and the number of metastatic lymph nodes (95, 96)
doi: 10.1152/physrev.00044.2023
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Adequate B12 is linked to better concentration, faster recall, and reduced brain fog, especially in adults over 40, in anyone on a plant-forward diet, and in patients with the MTHFR gene variant that affects how the body processes folate and B12
While the overall risk appears to be small, I now screen more carefully for patients with risk factors such as pre-existing optic nerve problems, glaucoma, or significant diabetic retinopathy. Recent research also connects liraglutide, the active ingredient in Saxenda and Victoza, to similar concerns