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Freezing can damage the protein structure of the medication, rendering it ineffective or potentially harmful

doi: 10.1016/j.tins.2008.09.001 181 RealiC.MagliozziR.RoncaroliF.NicholasR.HowellO

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Where specific remedies and management strategies are referenced, recommendations are based on standard medical practice guidelines from Mayo Clinic, Cleveland Clinic, Johns Hopkins Medicine, and peer-reviewed research