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Targeted deletion of Sec-tRNA [Ser]Sec ( Trsp ) gene in osteochondroprogenitor cells from embryonic stage caused the depletion of selenoproteins in skeletal systems, causing growth retardation, abnormalities in the epiphyseal growth plate, delayed endochondral ossification, and chondronecrosis, which recapitulated the major pathological features of KBD 73

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PMID: 37985817 Nat Aging Aging induces region-specific dysregulation of hormone synthesis in the primate adrenal gland

& Manolopoulos, V

This well-characterized peptide has attracted significant scientific interest due to its involvement in cellular signaling, extracellular matrix regulation, and tissue remodeling pathways

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