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Observations in rodent studies suggest that increases in bone mineral content may reflect structural adaptations, rather than changes in volumetric bone density

Rare but serious events have been reported, including prolonged erections/priapism, systemic reactions, neurological symptoms, kidney-related complications, and melanoma or concerning skin changes

Overall, acne caused by skin purging often tends to appear and then disappear much faster than classic breakouts

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High DNA fragmentation has been linked to reduced fertilisation rates, poorer embryo development, and higher miscarriage rates