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Glaxo Smith Kline sponsored meta analysis phase III randomized clinical trials, with a study duration of 2 years demonstrated that in a population with symptomatic BPH and/or at increased risk of prostate cancer, a statistically significant lower number of detectable prostate cancers was found in men taking dutasteride compared to control groups

Its lipid-improving efficacy has been utilized in hypercholesterolemia treatment

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Elevation of IL-1 and IL-6 has been shown to contribute to autoimmune disease by activating Th17 cells and suppressing regulatory T cells (88, 101) ( Figure 4 )