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Niacinamide : Helps in improving skin elasticity, enhancing the barrier function, evening out skin tone, and reducing dullness

Yang L, Yan S, Zhang Y, et al

10.1021/acschemneuro.7b00275 ACS Chem

As the authors point out, these findings may help to explain why these metabolic abnormalities occur in a cluster (such as found in the metabolic syndrome), partly because people are exposed to low doses of various POPs simultaneously

N.UdgaonkarJ

Admittedly, this is difficult given the complexities and lack of measurement techniques, and most evidence supporting this theory to date is based on mathematical approaches/modelling