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"Many patients notice initial improvement in overall skin tone and brightness with some lightening of dark spots within four to six weeks, but more significant changes in overall complexion and clarity often take three to four months of consistent use," she explains

The typical initiation dose is 2.5 mg weekly for four weeks, with gradual titration every four weeks based on individual response and tolerability

Beyond Wegovy, there are several other new, highly effective GLP-1s and GLP-1 combination medications approaching FDA approval

Morning testosterone may be appropriate if low libido or other features of hypogonadism are present

This helps maintain a more consistent skin tone and may prevent the formation of new dark spots

90 mg: -1.02%, p=0.001), BW (45 mg: -3.51%, p=0.0019