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It's reversible if side effects become intolerable

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Modify your eating habits Eat smaller, more frequent meals: Dont try to eat normal portions

Given the natural fluctuations in hormone levels and the intricate rhythms of human physiology throughout the day and over a persons lifetime, there is concern about the uncertain health ramifications of sustained elevation of incretin activity over decades of treatment

So he was really meaning shit all the time

These improvements were defined as "a drop in estimated glomerular filtration rate -- a measure of how much blood the kidneys filter clean every minute -- of at least 50%," according to the news release