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Although decidualization defects, immune perturbations, and matrix remodeling abnormalities have each been characterized in the context of normal implantation biology, their convergence and co-occurrence in RIF and RM patients reveals a qualitatively distinct pathological landscape

ASAT decreased by 13-43% depending on dose and treatment length

The drawbacks of conventional chemotherapy, such as severe toxicity, lack of specificity related to actively dividing cells, and resistance, can warrant the urgent need to develop an alternative approach to treat this disease

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With a 5-year overall survival of barely 510% and the highest incidence-to-mortality ratio of any solid tumor, PC has one of the highest mortality rates among cancers [68]