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In diet-induced obesity (DIO) models, NNMT loss-of-function and selective small-molecule inhibitors reduce white adipose mass and improve metabolic parameters without overt toxicity, positioning NNMT as a tractable target for metabolic-disease research [24]

He argues 'Nowhere was this truer than with antisera prepared against porcine glucagon the only type of glucagon then available to researchers wishing to prepare reagents suitable for immunoassay

But the dedicated cardiovascular outcomes trial doesnt read out until around 2029

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