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Pinecrest FL Table of Contents: What does semaglutide GLP-1 do to your body

Endocrinology 150 , 11741181 (2009)

Glucagon-like peptide-1 (GLP-1) is a naturally occurring hormone produced primarily by specialised L-cells in the lining of your small intestine and colon

35 Although these CVOTs were not specifically powered to detect differences in HF outcomes, they provided the first valuable signs of the benefit of GLP-1RAs in patients with HF

Figure 27: Photograph of Sir James Black (1924-2010), credit: Lyall

It remains unclear whether the imbalanced pharmacology or the longer half-life of tirzepatide contributes to its superior efficacy in glucose and weight reduction compared to the more balanced dual agonist, NNC0090-2746