None of the approved GLP-1 or dual-agonist products carries a dermatologic indication, and the largest relevant real-world study, a target trial emulation with matched cohorts of 169,630 each, found no significant differences for inflammatory or autoimmune skin outcomes other than psoriasis, pemphigus and bullous pemphigoid after correction for multiple testing
Sacpic staining showed that the proportions of total, primary, and secondary active hair follicles in the KO group, were significantly higher than that in the control group
Guanabenz enhances eIF2 phosphorylation, strengthens PERK pathway signaling, protects mice from cytokine shock, and reduces autoimmune symptoms in lupus models
If you are taking Ozempic alongside insulin or sulfonylureas, be aware that the risk of hypoglycaemia is increased and dose adjustments may be needed
Growing evidence supports the positive impact of GLP-1 RAs in reducing hepatic cytolysis enzymes [56,61,69,70,71,72,73,74,75,76,77,78,79,80,81] (Table 2)
Marrie RA, Walld R, Bolton JM et al (2017) Increased incidence of psychiatric disorders in immune-mediated inflammatory disease
