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Hypertension is the most common preventable risk factor for CVDs (including coronary heart disease, heart failure, stroke, myocardial infarction, atrial fibrillation, and peripheral artery disease), chronic kidney disease, and cognitive impairment, and also the main single factor for deaths and disability worldwide (133)

The effect of DPP-4 inhibitors, GLP-1 receptor agonists and SGLT-2 inhibitors on cardiorenal outcomes: a network meta-analysis of 23 CVOTs

doi: 10.1038/304368a0 14 HansenLDeaconCFOrskovCHolstJJ

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The introduction of vaccines, the introduction of penicillin, the introduction of insulin for diabetes: All these medical revolutions needed system-wide support to reach their full potential

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