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Naltrexone was originally developed in the 1980s as an FDA-app r oved treatment for opioid and alcohol addiction

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Afterwards, the correction equation of hepatic CL int was established for in vitro metabolism experiments (Poulin and Haddad, 2013)

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A synthetic pentadecapeptide frequently researched for its involvement in angiogenic processes , cellular protection mechanisms , and complex peptide signaling