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Description

While we found no studies describing the effects of bombesins on submucosal gland activation and/or regulation of muc5B in asthma, its ability to modulate glycoprotein secretion from whole tracheas under normal physiological conditions [201] suggests a potential role for it in pathophysiological conditions

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Supporters also heard from clinicians and patients who described perceived benefits and the lack of satisfactory options for some difficult conditions

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These reductions represented estimated treatment differences ranging from 3.0% to 7.8% weight loss versus placebo, all of which were statistically significant

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Eur Respir J 37(6):14001410

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