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Clin Podiatr Med 19(4):483491 Kanitakis J (2002) Anatomy, histology and immunohistochemistry of normal human skin

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The Charlton comorbidity index (CCI) and clinical frailty score (CFS) were calculated to determine the 10-year survival prognosis and frailty, respectively

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22 This demonstrates that epicardial fat tissue promotes atherogenesis through inflammation, biological dysfunction and paracrine effects through a mechanism other than traditional risk factors (e.g., metabolic syndrome, insulin resistance and abdominal visceral fat)

This raises the possibility that GLP-1s could influence the gut-immune axis, which is often disrupted in autoimmune diseases