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Anaphylaxis to intravenous furosemide

In murine studies, deletion of the IGF-1R in skeletal muscle resulted in glucose intolerance issues ultimately leading to T2D at an early age, because, although they express insulin receptors, they cannot form hybrid or IGF-1 receptors [162]

doi: 10.1038/s41588-021-00927-7 98 NicholsonJGFineHA

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While HRT remains a conventional option, it comes with potential risks, including cardiovascular issues and breast cancer concerns

Yang et al., 2018)