Matza LS, Stewart KD, Land LF, Patel H, Boye KS
10:e8166
In A Study of Olezarsen Administered to Patients With Familial Chylomicronemia Syndrome (BALANCE), 66 patients with genetically confirmed FCS (homozygous or heterozygous compound loss function mutations in the genes for LPL, apoC2, apoA5, LMF-1 , or GPIHBP1 ) and fasting TG 880 mg/dl ( 10 mmol/l) were randomized to receive placebo or olezarsen at 50 or 80 mg monthly [106]
Your clinician may discuss whether you are due to titrate up, since the reward effect tends to be stronger at 1 mg to 2 mg, or whether another factor explains the change
Longer-term studies are still needed to evaluate sustained efficacy and safety beyond 72 weeks
High-quality medications : The GLP-1 medications you buy from Canada are manufactured by similar companies as in the U.S., ensuring similar safety and effectiveness