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These fractions are known to exhibit chemotherapy resistance and possess the highest leukemogenic ability 25 , making them crucial targets for understanding disease progression and developing effective treatments

Knoepfler warned of placebo effects

Excessive daytime sleepiness (narcolepsy)

Cholesterol and lipid profile: moderate evidence Alpha-lipoic acid (ALA) may help support a healthier lipid profile by reducing total cholesterol and triglyceride levels especially in individuals with metabolic disorders like type 2 diabetes or metabolic syndrome

Most early discomfortnausea, cramping, constipationdoes not require stopping treatment and typically improves with simple adjustments