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However, GSAAT(C190S) accumulated to a lesser extent than any of the other mutants, albeit still more than that expressed in the gsa2 mutant

The present study demonstrated that CP treatment develops HC with associated histopathological changes, CNP upregulation, increased hepatic pro-inflammatory cytokines and oxidative stress, and Augmented protein levels of NF-B, and MAPKs

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This paper reports a remyelination screening platform based on mouse epiblast-derived OPCs to identify two FDA-approved compounds, miconazole and clobetasol, that enhance remyelination