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Since GLP-1 medications already slow digestion and can cause nausea, vomiting, and diarrhea, adding laxatives or diuretics creates a significant dehydration and electrolyte depletion risk

Med Sci Sports Exerc 24:12901297 Acknowledgments We would like to thank Beatrice Vetter, Liliane Todesco and Rjane Morand for performing biochemical analyses

These products may increase heart rate and blood pressure, potentially exacerbating cardiovascular risks

This educational guide reviews mechanisms, evidence quality, side effects, dosage context, administration routes, FDA status, and safety limitations

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Variations in the GLP1R gene (rs6923761) and MC4R gene (rs17782313) affect appetite signaling pathways, meaning some individuals experience robust weight loss at lower doses while others require higher amounts