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[8] [9] For weight management, NICE technology appraisals (TA875 for semaglutide [Wegovy] and TA664 for liraglutide [Saxenda]) provide specific eligibility criteria

Their effectiveness depends heavily on regular, sustained use

Retatrutida is a new-generation investigational peptide that acts as a triple agonist for GLP-1, GIP and glucagon receptors

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Efficacy and safety of liraglutide versus placebo as add-on to glucose-lowering therapy in patients with type 2 diabetes and moderate renal impairment (LIRA-RENAL): a randomized clinical trial