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No adverse effects were reported, but rigorous, large-scale trials are lacking, according to NIH

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The commenters noted that the cost of the procedure exceeds payment by approximately $4,000 and expressed concern that this discrepancy would result in patient access to the procedure being limited, particularly considering that the alternatives for severe emphysema patients involve much more invasive and expensive treatment options

Researchers actively investigate its potential role in cartilage regeneration

In preclinical studies, it has demonstrated a compelling range of effects, most notably its ability to promote angiogenesis