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Absolute deficiency occur up to 6% of those aged 60 years and older, whereas marginal deficiency occur in close to 20% of patients in later life ( Pernicious anemia is an autoimmune gastritis resulting from the destruction of gastric parietal cells and consequent impairment of intrinsic factors secretion to bind the ingested vitamin B12

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Briefly, as described (42), passage obstruction scored 03 (according to the loop diameters ratio close to anastomosis, loop diameters orally/loop diameters aborally = 1 passage is normal (score 0), between 1 and 1.33 is the sign of mild obstruction (score 1), between 1.33 and 1.66 is moderate obstruction (score 2), and more than 1.66 is severe obstruction (score 3))

Simon SL, McWhirter L, Diniz Behn C, et al

However, experts recommend getting your vitamin B12 from food, before trying a supplement