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A likely possibility is that homoglutathione replaces glutathione as the dominant cellular redox-buffer in tissues associated with nitrogen fixation, as homoglutathione is required for proper development of nodules (Frendo et al., For biosynthesis of glutathione and homoglutathione share a common first reaction, i.e., the synthesis of -glutamylcysteine, but the chemical diversity results from altered specificity for the nucleophilic amino acid in the second reaction of the pathway

doi: 10.3389/fimmu.2017.00356 116 AhernDJBrennanFM

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Legault Z, Bagnall N, Kimmerly DS

Age-dependent decrease in glutamine synthetase expression in the hippocampal astroglia of the triple transgenic Alzheimers disease mouse model: mechanism for deficient glutamatergic transmission

Choudhary, P