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Leptin exhibits clear pro-carcinogenic effects by promoting systemic inflammatory responses and cellular proliferation, while inhibiting apoptosis and immune surveillance functions, whereas adiponectin exerts the opposite effects [11]

The gel forming ability of glucan in the small intestine helps slow down the interactions of the digestive enzymes with nutrients and slows down the degradation and absorption of glucose and other nutrients leading a reduced peak postprandial blood glucose concentration for a short period of time [63]

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This is consistent with previous reports showing upregulation of genes responsible for amino acid catabolism, specifically D-serine deaminase ( dsdA ) when UPEC were grown in human urine 37,39