I was like, I got a train to get ready for it
Methylation issues are very common (up to 40% of patients) and many patients unknowingly supplement with cyanocobalamin which may increase serum levels but will not improve symptoms 5
It also promotes better sleep and lots more
It means that the evidence is promising but incomplete, and individuals should make informed decisions with appropriate medical guidance rather than treating preclinical results as established clinical fact
The most common method, also introduced by Schilling, is to inject a high dose of unlabeled B12 to saturate all binding capacities of the B12 binding proteins, and thereby facilitating urinary excretion of the absorbed radioactively labeled B12
For dietary deficiencies, maintenance injections continue until the issue resolves, with periodic testing to monitor your levels