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SURMOUNT-1 reported up to 20 to 22% weight reduction at the maximum 15 mg dose over 72 weeks
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In the Semaglutide Unabated Sustainability in Treatment of Type 2 Diabetes (SUSTAIN) clinical trial programme, semaglutide 1 mg was associated with greater reductions in glycated haemoglobin (HbA1c) and weight than exenatide extended-release 2 mg [7], dulaglutide 1.5 mg [8] and liraglutide 1.2 mg [9]
Attention to the side effects of these drugs has focused on gastrointestinal symptoms, but bone health is an area where research is still early and conflicting
Do not freeze semaglutideif the medication has been frozen, it must be discarded
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