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This situation feels different from other drug classes because it is: diabetes and obesity are massive markets, and beyond the FDA approved indicated populations, theres a swath of people interested in getting their hands on GLP-1 agonists off-label to help them lose a few extra pounds

Oral and nasal NAD+ options, such as Synchronicity Healths NAD+ Nasal Spray , tend to be easier to tolerate

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It may also decrease glucose-stimulated insulin secretion (GSIS), potentially leading to neonatal glucose dysregulation and associated risks

Who should avoid GLP-1