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Currently, the only GLP-1s that are FDA approved for chronic weight management in people without diabetes are Wegovy (semaglutide) and Saxenda (liraglutide)as long as patients meet certain criteria

References: Chen L, Zhu Y, Hu Z, Wu S, Jin C

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XG: Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writingoriginal draft, Writingreview and editing

Propionic acidemia is an autosomal recessive disorder that results from mutations in either of the two genes encoding the subunits of the mitochondrial enzyme, propionyl-CoA carboxylase (PCC)

Mitochondrial accumulation of APP and Abeta: significance for Alzheimer disease pathogenesis